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PMID: 20 WangMShiJYuCZhangXXuGXuZet al

The studys objectives are to characterize the safety, pharmacokinetics, and tolerability of NPM-139 to support the initiation of a Phase 2 dose-ranging study pending successful results of the Phase 1 study

In consideration of the renal site of action and the associated osmotic diuresis, a negative sodium balance has been postulated during SGLT2i administration

9.4 GSH-mediated immunotherapy Cancer immunotherapies, such as vaccines and immune checkpoint inhibitors, are most effective when their activity is confined to tumor sites

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